485 West Street, Amherst, MA     –     (413) 230-5121

Mission Cantina

Serving Amherst, MA Since 2011

Serving Amherst, MA Since 2011

Our vibrant cantina, located just south of downtown Amherst, MA, is your destination for fresh, authentic cooking and bold flavors. We pair exquisite house margaritas with an authentic menu featuring Mexican favorites like tacos, burritos, enchiladas, and more—each crafted with the freshest ingredients and your choice of filling. Whether you’re craving the perfect balance of spice and flavor or simply want to enjoy a casual night out, Mission Cantina delivers an unforgettable dining experience that’s as vibrant as our food and drinks.

We say NO to canola oil, NO to seed oils, NO to low-quality booze, and absolutely NO to fake mixers. Does it take more time? YES! But that’s exactly why it’s so good. We think you deserve the little guy who cuts up a fresh, juicy mango for your drink, instead of relying on mango-flavored alcohol.

Both of our restaurants are now taking reservations, and we’re here for you with delivery and takeout options, too. Fresh, real, and made with love—because you deserve nothing less.

Opening Hours

Mon: Closed

Tue: Closed

Wed: 4:00pm-9:00pm

Thu: 4:00pm-9:00pm

Fri: 4:00pm-9:00pm

Sat: 4:00pm-9:00pm

Sun: 4:00pm-9:00pm

Dine in Or Take Out

Exciting, authentic Mexican cuisine is never too far out of reach! Our specials change daily to include only the freshest products. We currently offer delivery service through GrubHub and Delivery Express!

Fresh.

Authentic.

Handcrafted.

Our Food

Craving authentic flavors and a vibrant dining experience? Come taste the bold, fresh, and unforgettable dishes at Mission Cantina in Amherst – your new go-to for satisfying every craving!

Our location

Step into Mission Cantina in Amherst, where every wall tells a story and every corner bursts with culture. Discover vibrant art, authentic flavors, and an ambiance that brings the spirit of Mexico to life—your visit awaits!

Our Reviews